Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | EYA2 | O00167 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SGK1 | O00141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879603 | 1.00 | MAPT (0.49) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879919 | 0.93 | LMNA (0.45) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879923 | 0.93 | LMNA (0.45) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5880285 | 0.91 | LMNA (0.49) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5880282 | 0.91 | LMNA (0.49) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879910 | 0.90 | LMNA (0.51) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879907 | 0.90 | LMNA (0.51) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879904 | 0.90 | KMT2A (0.52) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879902 | 0.90 | KMT2A (0.52) | MAPTALDH1A1LMNAHTTKDM4E | |
| SCHEMBL5879797 | 0.89 | MAPT (0.62) | MAPTALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026339-B2 | Inhibitors of HCV NS5B polymerase | PFIZER INC. | 2006-04-11 | — | — | US | disclosed |