Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.61 |
| ▸ | ITGAV | P06756 | 12/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879698 | 0.94 | ITGB3 (0.71) | ITGB3ITGAVTSHRNPC1RAB9A | |
| SCHEMBL5879625 | 0.90 | ITGB3 (0.61) | ITGB3ITGAVTSHRNPC1RAB9A | |
| SCHEMBL5879845 | 0.83 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL5879789 | 0.81 | ITGB3 (0.44) | ITGB3ITGAVSMN1; SMN2KDM4ECASP1 | |
| SCHEMBL5879538 | 0.80 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL5879791 | 0.77 | ITGB3 (0.74) | ITGB3ITGAV | |
| SCHEMBL5879843 | 0.76 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5879531 | 0.75 | ITGB3 (0.75) | ITGB3ITGAV | |
| SCHEMBL5879553 | 0.75 | ITGB3 (0.47) | ITGB3ITGAVKDM4EPOLB | |
| SCHEMBL5879558 | 0.74 | ITGB3 (0.74) | ITGB3ITGAVKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |