Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.74 |
| ▸ | ITGAV | P06756 | 10/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879562 | 0.86 | ITGB3 (0.56) | ITGB3ITGAV | |
| SCHEMBL5879621 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879569 | 0.82 | ITGB3 (0.51) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879664 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVKDM4EGAA | |
| SCHEMBL5028382 | 0.75 | ITGB3 (0.70) | ITGB3ITGAV | |
| SCHEMBL5879751 | 0.75 | ITGB3 (0.49) | ITGB3ITGAVKDM4ETHRBGAA | |
| SCHEMBL5879645 | 0.74 | ITGB3 (0.61) | ITGB3ITGAVKDM4EPOLB | |
| SCHEMBL5879680 | 0.73 | ITGB3 (0.46) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879553 | 0.72 | ITGB3 (0.47) | ITGB3ITGAVKDM4EPOLBGAA | |
| SCHEMBL5879778 | 0.72 | ITGB3 (0.43) | ITGB3ITGAVKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |