Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 1.00 |
| ▸ | ITGAV | P06756 | 18/20 | 1.00 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879843 | 0.86 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5879543 | 0.86 | ITGB3 (0.76) | ITGB3ITGAVNAMPT | |
| SCHEMBL5879684 | 0.84 | ITGB3 (0.73) | ITGB3ITGAVCDC25A | |
| SCHEMBL5879746 | 0.79 | ITGB3 (0.65) | ITGB3ITGAVCDC25A | |
| SCHEMBL5879552 | 0.78 | ITGB3 (0.83) | ITGB3ITGAV | |
| SCHEMBL5880224 | 0.76 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5879531 | 0.73 | ITGB3 (0.75) | ITGB3ITGAVNAMPT | |
| SCHEMBL5879584 | 0.71 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL5879698 | 0.70 | ITGB3 (0.71) | ITGB3ITGAVNAMPT | |
| SCHEMBL5879561 | 0.69 | ITGB3 (0.70) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |