Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.65 |
| ▸ | ITGAV | P06756 | 13/20 | 0.65 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879666 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVCDC25A | |
| SCHEMBL17260671 | 0.77 | TDP1 (0.66) | TDP1L3MBTL1SIGMAR1 | |
| SCHEMBL5879684 | 0.73 | ITGB3 (0.73) | ITGB3ITGAVCDC25A | |
| SCHEMBL5879575 | 0.71 | ITGB3 (0.51) | ITGB3ITGAVCDC25A | |
| SCHEMBL29531485 | 0.69 | CA1 (0.62) | TDP1L3MBTL1SIGMAR1 | |
| SCHEMBL17550101 | 0.69 | CA1 (0.62) | TDP1L3MBTL1SIGMAR1 | |
| SCHEMBL5879576 | 0.66 | ITGB3 (0.54) | ITGB3ITGAVCDC25A | |
| SCHEMBL1163856 | 0.65 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL1163877 | 0.65 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL5879512 | 0.65 | ITGB3 (0.44) | ITGB3ITGAVCDC25AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |