Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.67 |
| ▸ | ITGAV | P06756 | 11/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879535 | 0.91 | ITGB3 (0.75) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879963 | 0.85 | ITGB3 (0.90) | ITGB3ITGAV | |
| SCHEMBL5879524 | 0.80 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5879664 | 0.75 | ITGB3 (0.52) | ITGB3ITGAVKDM4ETP53 | |
| SCHEMBL5879521 | 0.75 | POLB (0.46) | ITGB3ITGAV | |
| SCHEMBL5879531 | 0.74 | ITGB3 (0.75) | ITGB3ITGAV | |
| SCHEMBL5879659 | 0.69 | ITGB3 (0.66) | ITGB3ITGAV | |
| SCHEMBL6424193 | 0.69 | ITGB3 (0.59) | ITGB3ITGAV | |
| SCHEMBL5879595 | 0.68 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL5879566 | 0.68 | ITGB3 (0.54) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |