Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGAV | P06756 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879751 | 0.80 | ITGB3 (0.49) | ITGB3ITGAVKDM4EGAAALDH1A1 | |
| SCHEMBL5879601 | 0.79 | HSD17B10 (0.45) | ITGB3ITGAVKDM4EALDH1A1TP53 | |
| SCHEMBL5879558 | 0.75 | ITGB3 (0.74) | ITGB3ITGAVKDM4EGAA | |
| SCHEMBL5879740 | 0.75 | ITGB3 (0.67) | ITGB3ITGAVKDM4ETP53 | |
| SCHEMBL5879692 | 0.75 | NOS2 (0.48) | ITGB3ITGAVKDM4EALDH1A1MEN1 | |
| SCHEMBL5879592 | 0.75 | ITGB3 (0.43) | ITGB3ITGAVALDH1A1TP53 | |
| SCHEMBL5879535 | 0.74 | ITGB3 (0.75) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879621 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879569 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVKDM4ELMNA | |
| SCHEMBL5879963 | 0.73 | ITGB3 (0.90) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |