Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TNKS | O95271 | 2/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273124 | 0.89 | PARP1 (0.67) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL3224273 | 0.82 | PARP1 (0.75) | KDM4EALDH1A1GAALMNAGLA | |
| SCHEMBL5879665 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL11519726 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL29360611 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL29641306 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL19289 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL11523430 | 0.75 | ALDH1A1 (0.95) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL28200023 | 0.75 | ALDH1A1 (0.95) | KDM4EALDH1A1GAALMNAGLA | |
| Acridone SCHEMBL3420574 | 0.75 | ALDH1A1 (0.95) | KDM4EALDH1A1GAALMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |