Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374046 | 0.83 | ALDH1A1 (0.46) | F10F2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3369734 | 0.83 | F10 (0.63) | F10F2 | |
| SCHEMBL3370092 | 0.81 | RAB9A (0.45) | F10KMT2AF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3369492 | 0.80 | ALDH1A1 (0.43) | F10F2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3369950 | 0.80 | F10 (0.43) | F10F2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL5880602 | 0.80 | RAB9A (0.46) | F10KMT2AF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3373004 | 0.80 | MOK (0.45) | F10KMT2AF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3368838 | 0.79 | ALDH1A1 (0.43) | F10F2ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3371312 | 0.78 | F10 (0.45) | F10KMT2AF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3367236 | 0.77 | F10 (0.61) | F10KMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006528213-A | — | — | 2006-12-14 | — | — | JP | claimed |
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | claimed |