SCHEMBL5880685

SCHEMBL5880685

CC1(OC(=O)O)C2CC3CC(C2)CC1C3

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.43
CYP19A1 P11511 2/20 0.43
HSD11B1 P28845 10/20 0.36
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5880684 0.84 CYP17A1 (0.44) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL439024 0.83 CYP17A1 (0.43) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL12847539 0.81 CYP17A1 (0.42) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL133979 0.81 CYP17A1 (0.42) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL8398065 0.80 CYP17A1 (0.40) CYP17A1CYP19A1HSD11B1MEN1KMT2A
SCHEMBL6249302 0.79 MAPK1 (0.33)
SCHEMBL13094606 0.79 CYP17A1 (0.41) CYP17A1CYP19A1HSD11B1MEN1KMT2A
SCHEMBL13288279 0.79 CYP17A1 (0.44) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL7745860 0.79 CYP17A1 (0.41) CYP17A1CYP19A1HSD11B1SCN1ASCN2A
SCHEMBL24064303 0.78 CYP17A1 (0.40) CYP17A1CYP19A1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7108953-B2 Dissolution inhibitors in photoresist compositions for microlithography E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-09-19 US claimed
US-20050260519-A1 Dissolution inhibitors in photoresist compositions for microlithography E. I. DU PONT DE NEMOURS AND COMPANY 2005-11-24 US claimed
CN-1470010-A Dissolution inhibitors in photoresist compositions for microlithography 纳幕尔杜邦公司 2004-01-21 CN claimed
EP-1325387-A2 DISSOLUTION INHIBITORS IN PHOTORESIST COMPOSITIONS FOR MICROLITHOGRAPHY E.I. Dupont de Nemours and Company (US) 2003-07-09 EP claimed
WO-2002031595-A2 DISSOLUTION INHIBITORS IN PHOTORESIST COMPOSITIONS FOR MICROLITHOGRAPHY E.I. DUPONT DE NEMOURS AND COMPANY (US) 2002-04-18 WO claimed
US-20230152693-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-18 US disclosed