SCHEMBL5881409

SCHEMBL5881409

C=C(C)C(=O)N[SiH2]N(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5881346 0.76 ALDH1A1 (0.33) TGFBR1ALDH1A1
SCHEMBL9798528 0.68 ALDH1A1 (0.36) TGFBR1ALDH1A1
SCHEMBL28972965 0.67
SCHEMBL27525063 0.67 KDM4E (0.37) TGFBR1ALDH1A1
SCHEMBL27555247 0.65 ALDH1A1 (0.37) TGFBR1ALDH1A1
N,N-Dimethylethanaminium SCHEMBL17910241 0.65 TGFBR1 (0.35) TGFBR1ALDH1A1
SCHEMBL5681532 0.64 TGFBR1 (0.38) TGFBR1ALDH1A1
SCHEMBL28049100 0.64 TGFBR1 (0.38) TGFBR1ALDH1A1
N,N-Dimethylethanaminium SCHEMBL446422 0.64 TGFBR1 (0.38) TGFBR1ALDH1A1
SCHEMBL888113 0.64 TGFBR1 (0.34) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6994791-B2 Adsorbent material and method of preparing an adsorbent material AKZO NOBEL N.V. (NL) 2006-02-07 US disclosed
US-20040059040-A1 Adsorbent material and method of preparing an adsorbent material AKZO NOBEL N.V. (NL) 2004-03-25 US disclosed