SCHEMBL588241

SCHEMBL588241

FC(C(F)(F)F)C(F)(F)[S]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Apaflurane SCHEMBL19860 0.74 ALDH1A1 (0.33)
Apaflurane SCHEMBL7649343 0.70 ALDH1A1 (0.31)
Apaflurane SCHEMBL17867718 0.70 ALDH1A1 (0.31)
SCHEMBL143180 0.70
SCHEMBL1274333 0.67
Apaflurane SCHEMBL7649339 0.67
Apaflurane SCHEMBL5545395 0.67
SCHEMBL17158623 0.67
SCHEMBL23464977 0.65 ALDH1A1 (0.33)
SCHEMBL726552 0.65 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0596358-B1 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles BAYER AG (DE) 1998-10-28 EP claimed
EP-0596358-A1 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles BAYER AG (DE) 1994-05-11 EP claimed
EP-0093977-B1 2,5-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1987-08-05 EP claimed
EP-0093976-A1 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP claimed
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO disclosed
EP-4317160-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Kumiai Chemical Industry Co., Ltd. (JP) 2024-02-07 EP disclosed
WO-2023190286-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2023-10-05 WO disclosed
US-20230085307-A1 PYRIDAZINONE COMPOUND AND HERBICIDE NISSAN CHEMICAL CORPORATION (JP) 2023-03-16 US disclosed
WO-2022259985-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2022-12-15 WO disclosed
US-20220144775-A1 HYDRAZIDE COMPOUND AND KINASE INHIBITOR NISSAN CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
EP-3949731-A1 PYRIDAZINONE COMPOUND AND HERBICIDE Nissan Chemical Corporation (JP) 2022-02-09 EP disclosed
EP-3915636-A1 HYDRAZIDE COMPOUND AND KINASE INHIBITOR Nissan Chemical Corporation (JP) 2021-12-01 EP disclosed
EP-0597304-A1 Use of substituted benzimidazoles BAYER AG (DE) 1994-05-18 EP disclosed
EP-0596358-A1 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles BAYER AG (DE) 1994-05-11 EP disclosed
US-5264448-A Thioamides, oxazole ring, insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5206259-A Insecticides, acaricides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-27 US disclosed
EP-0394043-A1 An amide compound and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP disclosed
EP-0093977-B1 2,5-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BAYER AG (DE) 1987-08-05 EP disclosed
EP-0093977-A1 2,5-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP disclosed
EP-0093976-A1 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides BAYER AG (DE) 1983-11-16 EP disclosed