Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199936 | 0.97 | — | — | |
| Bromide SCHEMBL19637938 | 0.91 | — | — | |
| SCHEMBL28435098 | 0.85 | OPRM1 (0.50) | — | |
| SCHEMBL31067727 | 0.85 | — | — | |
| Bromide SCHEMBL19637945 | 0.80 | — | — | |
| SCHEMBL8667388 | 0.76 | — | — | |
| Bromide SCHEMBL5883831 | 0.73 | — | — | |
| Bromide SCHEMBL15772021 | 0.71 | — | — | |
| SCHEMBL38853 | 0.69 | — | — | |
| SCHEMBL22345156 | 0.69 | DNM1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112059202-A | Preparation method and application of silver-copper bimetallic nano-fiber | 昆明贵研新材料科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112059202-B | Preparation method and application of silver-copper bimetallic nano-fiber | 昆明贵研新材料科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-110480028-B | Method for preparing silver nano-fibers by using organic halide as auxiliary material and application thereof | 昆明贵研新材料科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112059202-A | Preparation method and application of silver-copper bimetallic nano-fiber | 昆明贵研新材料科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-6989392-B2 | 2-Aminoquinolines as melanin concentrating hormone receptor antagonists | ABBOTT LABORATORIES (US) | 2006-01-24 | — | — | US | disclosed |
| US-20040063756-A1 | 2-Aminoquinolines as melanin concentrating hormone receptor antagonists | ABBVIE INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2003105850-A1 | 2-AMINOQUINOLINES AS MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2003-12-24 | — | — | WO | disclosed |