Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201631 | 0.83 | MAPT (0.66) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL5884071 | 0.80 | PPARG (0.67) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL5884072 | 0.80 | PPARG (0.67) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL6157752 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL4748573 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL209831 | 0.75 | HRH3 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL6805395 | 0.74 | PPARG (0.67) | ALDH1A1KDM4EMAPTPKMHTT | |
| Hydrochloric Acid SCHEMBL5692377 | 0.74 | HRH3 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL7160719 | 0.73 | MAPT (0.63) | ALDH1A1KDM4EMAPTPKMHTT | |
| SCHEMBL7160716 | 0.73 | MAPT (0.63) | ALDH1A1KDM4EMAPTPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001910-B1 | Thiazolidinedione derivatives as antidiabetic agents | VITA-INVEST S.A. (ES) | 2006-02-21 | — | — | US | disclosed |
| EP-1231211-B1 | THIAZOLIDINEDIONE DERIVATIVES AS ANTIDIABETIC AGENTS | VITA INVEST SA (ES) | 2003-05-28 | — | — | EP | disclosed |
| EP-1231211-A1 | THIAZOLIDINEDIONE DERIVATIVES AS ANTIDIABETIC AGENTS | VITA-INVEST, S.A. (ES) | 2002-08-14 | — | — | EP | disclosed |