Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884590 | 0.92 | KCNH2 (0.35) | HRH3HPGDMAP4K4MAPTGPR119 | |
| SCHEMBL5884443 | 0.91 | MAP4K4 (0.36) | MAP4K4MAPTCXCR3ALDH1A1LMNA | |
| SCHEMBL5884348 | 0.90 | MAPT (0.37) | HRH3MAPTGPR119CXCR3 | |
| SCHEMBL5884436 | 0.90 | FFAR1 (0.33) | HRH3MAP4K4MAPTIDH1CTSS | |
| SCHEMBL5884551 | 0.88 | HRH3 (0.33) | HRH3HPGDIDH1PTGES | |
| SCHEMBL5884636 | 0.83 | DRD4 (0.34) | MAP4K4CXCR3SLC6A9KMT2APTGS1 | |
| SCHEMBL5883978 | 0.82 | KMT2A (0.39) | HRH3MAP4K4KMT2APTGS1PTGS2 | |
| SCHEMBL5884946 | 0.82 | MEN1 (0.33) | IDH1SLC6A9KMT2APTGS1PTGS2 | |
| SCHEMBL5884768 | 0.81 | FFAR1 (0.39) | MAP4K4MAPTALDH1A1LMNAPTGS1 | |
| SCHEMBL5884929 | 0.80 | DRD4 (0.33) | MAP4K4PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |