Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.34 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884443 | 0.92 | MAP4K4 (0.36) | DRD4DRD2MAP4K4NR1I2KMT2A | |
| SCHEMBL5884929 | 0.91 | DRD4 (0.33) | DRD4DRD2MAP4K4NR1I2RBP4 | |
| SCHEMBL5884590 | 0.91 | KCNH2 (0.35) | MAP4K4KMT2AKCNH2SLC6A9CXCR3 | |
| SCHEMBL5884232 | 0.90 | FFAR1 (0.38) | DRD4DRD2MAP4K4RBP4TTR | |
| SCHEMBL5884463 | 0.86 | CYP1A2 (0.37) | DRD4DRD2MAP4K4NR1I2KMT2A | |
| SCHEMBL5884176 | 0.83 | HRH3 (0.37) | MAP4K4KMT2ASLC6A9PTGS1PTGS2 | |
| SCHEMBL5884360 | 0.83 | MAPT (0.36) | KMT2AKCNH2CXCR3 | |
| SCHEMBL5884551 | 0.82 | HRH3 (0.33) | — | |
| SCHEMBL5884870 | 0.82 | FFAR1 (0.36) | DRD4DRD2MAP4K4RBP4TTR | |
| SCHEMBL5884768 | 0.82 | FFAR1 (0.39) | DRD4DRD2MAP4K4RBP4TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |