Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884232 | 0.93 | FFAR1 (0.38) | FFAR1TLR4TLR2TTRRBP4 | |
| SCHEMBL5884436 | 0.92 | FFAR1 (0.33) | FFAR1DRD2DRD3MAP4K4ALDH1A1 | |
| SCHEMBL5884443 | 0.89 | MAP4K4 (0.36) | FFAR1TTRRBP4DRD2DRD4 | |
| SCHEMBL5884870 | 0.89 | FFAR1 (0.36) | FFAR1TLR4TLR2TTRRBP4 | |
| SCHEMBL5884368 | 0.87 | NPC1 (0.38) | TLR4TLR2DRD2DRD4MAP4K4 | |
| SCHEMBL5884946 | 0.84 | MEN1 (0.33) | FFAR1TLR4TLR2DGAT1DRD2 | |
| SCHEMBL5884473 | 0.83 | FFAR1 (0.38) | FFAR1DGAT1ALDH1A1LMNAPOLB | |
| SCHEMBL5884636 | 0.82 | DRD4 (0.34) | FFAR1TTRRBP4DRD2DRD4 | |
| SCHEMBL5884176 | 0.81 | HRH3 (0.37) | MAP4K4PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL5884909 | 0.81 | GAA (0.31) | FFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |