Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884674 | 0.90 | GPR119 (0.38) | GPR119PANK3ACACBTEAD1TEAD3 | |
| SCHEMBL5884332 | 0.86 | KMT2A (0.39) | GPR119GAATEAD1TEAD3KMT2A | |
| SCHEMBL5884268 | 0.86 | MEN1 (0.43) | GPR119PANK3KMT2AALDH1A1 | |
| SCHEMBL5884362 | 0.82 | NR1I2 (0.38) | GPR119GAAACACBTEAD1TEAD3 | |
| SCHEMBL5884759 | 0.81 | MEN1 (0.43) | PANK3KMT2AALDH1A1HRH3L3MBTL1 | |
| SCHEMBL5884624 | 0.79 | GPR119 (0.44) | GPR119GAAACACBKCNH2 | |
| SCHEMBL5884475 | 0.78 | TDP1 (0.41) | GAATEAD1TEAD3ALDH1A1L3MBTL1 | |
| SCHEMBL5884356 | 0.77 | HRH3 (0.38) | GPR119GAAHPGDHRH3L3MBTL1 | |
| SCHEMBL5883827 | 0.77 | KMT2A (0.40) | GPR119PANK3KMT2AALDH1A1KCNH2 | |
| SCHEMBL5884253 | 0.77 | KMT2A (0.40) | GPR119PANK3KMT2AALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |