SCHEMBL5884624

SCHEMBL5884624

CCc1cnc(N2CCC(CCOc3ccc(C=NOC)cc3)CC2)nc1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 15/20 0.44
KCNH2 Q12809 2/20 0.40
ACACB O00763 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5884893 0.91 GPR119 (0.44) GPR119KCNH2ACACB
SCHEMBL5884475 0.83 TDP1 (0.41) GAA
SCHEMBL5884332 0.79 KMT2A (0.39) GPR119GAA
SCHEMBL5884262 0.79 GPR119 (0.37) GPR119KCNH2ACACBGAA
SCHEMBL5884362 0.78 NR1I2 (0.38) GPR119ACACBGAA
SCHEMBL5883969 0.78 MAPT (0.39) KCNH2
SCHEMBL5884261 0.77 PPARG (0.37) GAA
SCHEMBL5884268 0.77 MEN1 (0.43) GPR119
SCHEMBL5884324 0.76 PPARG (0.46) GAA
SCHEMBL5884598 0.75 KCNH2 (0.36) GPR119KCNH2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7078403-B1 Antiviral agents BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) 2006-07-18 US claimed