SCHEMBL5884482

SCHEMBL5884482

NCCCCC(N)C(=O)N(C(=O)C(N)Cc1c[nH]cn1)C(CCCCN)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.38
CPB2 Q96IY4 7/20 0.34
CPB1 P15086 3/20 0.34
MMP2 P08253 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
MC4R P32245 2/20 0.31
MC5R P33032 1/20 0.31
MC3R P41968 1/20 0.31
ARG1 P05089 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30
DPP7 Q9UHL4 1/20 0.30
SLC15A2 Q16348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5598612 0.94 GSR (0.34) GSRCPB2CPB1ITGB3ITGA2B
SCHEMBL1959818 0.93 CPB2 (0.33) GSRCPB2CPB1ITGB3ITGA2B
SCHEMBL8781595 0.92 CPB2 (0.33) GSRCPB2CPB1
SCHEMBL259086 0.91 GSR (0.34) GSRCPB2CPB1ITGB3ITGA2B
SCHEMBL2356078 0.91 CPB2 (0.32) GSRCPB2CPB1
SCHEMBL15023743 0.91 GSR (0.35) GSRCPB2CPB1
SCHEMBL5598780 0.91 CPB2 (0.34) GSRCPB2CPB1
SCHEMBL5155910 0.90 GSR (0.33) GSRCPB2CPB1ITGB3ITGA2B
SCHEMBL9747723 0.90 MMP2 (0.42) GSRCPB2MMP2ITGB3ITGA2B
SCHEMBL27687342 0.90 GSR (0.31) GSRMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5470876-A Antialopecia, superoxide dismutase activity PROCTOR PETER H (US) 1995-11-28 US claimed
US-7037697-B2 Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD and use of the said SOD in cosmetic, food, and pharmaceutical compositions COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-05-02 US disclosed
US-20030064494-A1 Novel isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD and use of the said SOD in cosmetic, food, and pharmaceutical compositions COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2003-04-03 US disclosed
US-6485950-B1 Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-11-26 US disclosed
US-5470876-A Antialopecia, superoxide dismutase activity PROCTOR PETER H (US) 1995-11-28 US disclosed
EP-0327263-B1 Hair growth stimulation with nitroxide and other radicals PROCTOR PETER H (US) 1994-09-07 EP disclosed
EP-0327263-A1 Hair growth stimulation with nitroxide and other radicals PROCTOR, Peter H. (US) 1989-08-09 EP disclosed