Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884269 | 0.91 | DRD2 (0.40) | DRD2DRD1DRD3LTA4HDRD5 | |
| SCHEMBL5884173 | 0.90 | KMT2A (0.43) | DRD2DRD1DRD3DRD4LTA4H | |
| SCHEMBL5884502 | 0.87 | DRD2 (0.41) | DRD2DRD1DRD3LTA4HDRD5 | |
| SCHEMBL5884891 | 0.86 | DRD2 (0.39) | DRD2DRD1DRD3DRD4LTA4H | |
| SCHEMBL5883893 | 0.86 | AXL (0.41) | DRD2DRD1DRD3DRD4LTA4H | |
| SCHEMBL5884681 | 0.82 | DRD4 (0.43) | DRD2DRD1DRD3DRD4LTA4H | |
| SCHEMBL5884551 | 0.81 | HRH3 (0.33) | HRH3 | |
| SCHEMBL5884607 | 0.80 | KMT2A (0.47) | DRD2DRD1DRD3DRD4LTA4H | |
| SCHEMBL5884929 | 0.79 | DRD4 (0.33) | DRD2DRD4HTR1AHTR2A | |
| SCHEMBL5884360 | 0.77 | MAPT (0.36) | L3MBTL1ARKCNH2AOC3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |