Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885004 | 0.90 | HTR4 (0.42) | AXLHTR4BPTFPANK3SLC6A2 | |
| SCHEMBL5884042 | 0.89 | LMNA (0.42) | AXLHTR4DRD4BPTFSLC6A2 | |
| SCHEMBL5884891 | 0.89 | DRD2 (0.39) | DRD4SLC6A2SLC6A4LTA4HDRD2 | |
| SCHEMBL5884648 | 0.87 | HTR4 (0.42) | AXLHTR4DRD4BPTFPANK3 | |
| SCHEMBL5884836 | 0.86 | HTR4 (0.46) | AXLHTR4BPTFPANK3SLC6A2 | |
| SCHEMBL5884775 | 0.86 | DRD2 (0.39) | DRD4SLC6A2SLC6A4LTA4HDRD2 | |
| SCHEMBL5884258 | 0.85 | LMNA (0.36) | BPTFPANK3CYP1A2MAPTLMNA | |
| SCHEMBL5884681 | 0.85 | DRD4 (0.43) | HTR4DRD4SLC6A2SLC6A4LTA4H | |
| SCHEMBL5884712 | 0.84 | LMNA (0.36) | BPTFPANK3CYP1A2MAPTLMNA | |
| SCHEMBL5884533 | 0.83 | LMNA (0.38) | BPTFPANK3CYP1A2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |