Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | LCAT | P04180 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885023 | 0.92 | KCNH2 (0.37) | TEAD1TEAD3HRH3GPR119LCAT | |
| SCHEMBL5884831 | 0.91 | TEAD1 (0.36) | TEAD1TEAD3GPR119KCNH2MAPT | |
| SCHEMBL5884258 | 0.88 | LMNA (0.36) | TEAD1TEAD3SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5884514 | 0.86 | NR1I2 (0.35) | TEAD1TEAD3HRH3GPR119MAOB | |
| SCHEMBL5884712 | 0.84 | LMNA (0.36) | HRH3SMN1; SMN2MAPTHPGDL3MBTL1 | |
| SCHEMBL5884736 | 0.82 | SMN1; SMN2 (0.35) | GPR119SMN1; SMN2KCNH2MAPTBCHE | |
| SCHEMBL5884689 | 0.82 | KCNH2 (0.39) | TEAD1TEAD3GPR119SMN1; SMN2KCNH2 | |
| SCHEMBL5884333 | 0.82 | KCNH2 (0.39) | TEAD1TEAD3GPR119SMN1; SMN2KCNH2 | |
| SCHEMBL14191686 | 0.82 | NR1I2 (0.38) | TEAD1TEAD3GPR119KCNH2MAPT | |
| SCHEMBL5884133 | 0.80 | NR1I2 (0.36) | TEAD1TEAD3GPR119KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |