Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884586 | 0.91 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2DGAT1NPC1 | |
| SCHEMBL5884773 | 0.91 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2DGAT1NPC1 | |
| SCHEMBL5884910 | 0.90 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2DGAT1NPC1 | |
| SCHEMBL5884889 | 0.89 | NPC1 (0.37) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5884266 | 0.89 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL5884626 | 0.83 | KMT2A (0.44) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5884872 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5884751 | 0.81 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5884592 | 0.81 | NPC1 (0.35) | SMN1; SMN2DGAT1NPC1RAB9A | |
| SCHEMBL5884841 | 0.81 | CHRNB2 (0.34) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |