Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884889 | 0.92 | NPC1 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL5884903 | 0.90 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A2 | |
| SCHEMBL5884368 | 0.89 | NPC1 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL5884870 | 0.88 | FFAR1 (0.36) | TLR4TLR2DRD2DRD4BTK | |
| SCHEMBL5884872 | 0.82 | SMN1; SMN2 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL5884797 | 0.81 | CHRNB2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A2 | |
| SCHEMBL5884627 | 0.81 | L3MBTL1 (0.33) | NPC1RAB9ABTKSMN1; SMN2MAP4K4 | |
| SCHEMBL5884463 | 0.81 | CYP1A2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A2 | |
| SCHEMBL5884948 | 0.81 | MEN1 (0.39) | NPC1RAB9ATLR4TLR2CYP1A2 | |
| SCHEMBL5884927 | 0.81 | CHRNB2 (0.34) | CHRNB2CHRNA4CHRNB4CHRNA3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |