SCHEMBL5884967

SCHEMBL5884967

C=CC(C([NH])=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175982 0.82
Lithium SCHEMBL31299622 0.79 LMNA (0.39)
SCHEMBL28788958 0.79 LMNA (0.39)
SCHEMBL31299606 0.79 LMNA (0.39)
Charcoal, Activated SCHEMBL8053844 0.79 LMNA (0.39)
Potassium SCHEMBL31299607 0.79 LMNA (0.39)
SCHEMBL28238346 0.79 LMNA (0.39)
Ethyne SCHEMBL18186431 0.77 LMNA (0.37)
SCHEMBL6438822 0.77 LMNA (0.37)
Ethyne SCHEMBL10359508 0.77 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7071212-B2 N-(4-carbamimidoyl-phenyl)-glycine derivatives HOFFMANN-LA ROCHE INC. (US) 2006-07-04 US claimed