SCHEMBL5884975

SCHEMBL5884975

C=C(CC(C)(C)c1ccc(OC(C)=O)cc1)c1ccc(OC(C)=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.47
HSD17B10 Q99714 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 4/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ESR1 P03372 1/20 0.42
PGR P06401 1/20 0.42
CHRM2 P08172 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
AR P10275 1/20 0.42
CHRM1 P11229 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 2/20 0.41
PKM P14618 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20392009 0.83 ELANE (0.46) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL23842566 0.80 ELANE (0.44) ELANEHSD17B10ESR1CHRM2AR
SCHEMBL10204738 0.78 ELANE (0.55) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL25463194 0.78 ELANE (0.55) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL1787793 0.78 TDP1 (0.52) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL16795587 0.77 LMNA (0.55) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL11133412 0.77 LMNA (0.50) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL7620007 0.77 CYP3A4 (0.56) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL4517844 0.77 LMNA (0.50) ELANEHSD17B10KMT2AMEN1LMNA
SCHEMBL4543935 0.76 ELANE (0.51) ELANEHSD17B10KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022762-B2 Method of emulsion polymerization AGFA-GEVAERT (BE) 2006-04-04 US disclosed
US-20060009574-A1 Method of emulsion polymerization AERT HUUB V 2006-01-12 US disclosed
US-20050020787-A1 Method of emulsion polymerization E.I. DU PONT DE NEMOURS AND COMPANY 2005-01-27 US disclosed
US-20040176527-A1 Method of emulsion polymerization BARCLAYS BANK PLC, AS COLLATERAL AGENT 2004-09-09 US disclosed
EP-1217010-B1 Method of emulsion polymerization AGFA GEVAERT (BE) 2004-08-18 EP disclosed
EP-1217010-A1 Method of emulsion polymerization Agfa-Gevaert (BE) 2002-06-26 EP disclosed
US-20020072580-A1 Method of emulsion polymerization E.I. DU PONT DE NEMOURS AND COMPANY 2002-06-13 US disclosed
US-4059638-A Trisphenol process BAYER AKTIENGESELLSCHAFT (DT) 1977-11-22 US disclosed