Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ethyl Hydrogen Phosphonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Hydrogen Phosphonate SCHEMBL11598876 | 0.90 | KDM4E (0.36) | PPARDTSHRLPAR3LPAR1LPAR2 | |
| Ethyl Hydrogen Phosphonate SCHEMBL29833476 | 0.88 | ALDH1A1 (0.35) | TSHR | |
| Ethyl Hydrogen Phosphonate SCHEMBL28925 | 0.88 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL8406614 | 0.87 | KDM4E (0.35) | PPARDTSHRLPAR3LPAR1LPAR2 | |
| Ethyl Hydrogen Phosphonate SCHEMBL7193350 | 0.85 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL5449338 | 0.85 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL7183165 | 0.85 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL10454675 | 0.85 | — | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL8819664 | 0.85 | ALDH1A1 (0.33) | — | |
| Ethyl Hydrogen Phosphonate SCHEMBL21178179 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018977-B2 | Rinse-added fabric treatment composition, product containing same and methods thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-28 | — | — | US | disclosed |
| US-20060030515-A1 | Rinse-added fabric treatment composition, product containing same and methods and uses thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-02-09 | — | — | US | disclosed |
| EP-1504082-A1 | RINSE-ADDED FABRIC TREATMENT COMPOSITION AND METHODS AND USES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097781-A1 | RINSE-ADDED FABRIC TREATMENT COMPOSITION AND METHODS AND USES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-27 | — | — | WO | disclosed |
| US-20030216282-A1 | Rinse-added fabric treatment composition, product containing same and methods and uses thereof | THE PROCTER & GAMBLE COMPANY | 2003-11-20 | — | — | US | disclosed |