Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL588532 | 0.76 | KMT2A (0.36) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| Trifluoroacetic Acid SCHEMBL2672412 | 0.72 | GPR6 (0.36) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL4152368 | 0.70 | CETP (0.40) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL3948728 | 0.69 | CETP (0.42) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL2922890 | 0.69 | ALDH1A1 (0.48) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL588576 | 0.69 | KMT2A (0.43) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL588747 | 0.69 | CCR1 (0.39) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL588746 | 0.69 | CCR1 (0.39) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL588859 | 0.68 | ALDH1A1 (0.44) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA | |
| SCHEMBL29092505 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2MAPTCYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114878-B2 | 6,7-dihydrothieno[3,2-d]pyrimidine for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-14 | — | — | US | disclosed |