Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | C1S | P09871 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2672412 | 0.82 | GPR6 (0.36) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL590103 | 0.81 | MEN1 (0.37) | KMT2AMEN1HTTC1SDPP4 | |
| SCHEMBL4152368 | 0.77 | CETP (0.40) | KMT2ATSHRMAPTSMN1; SMN2CETP | |
| SCHEMBL588533 | 0.76 | SMN1; SMN2 (0.36) | KMT2AMEN1HTTTSHRDPP4 | |
| SCHEMBL588747 | 0.75 | CCR1 (0.39) | KMT2ATSHRMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL588746 | 0.75 | CCR1 (0.39) | KMT2ATSHRMAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL588576 | 0.71 | KMT2A (0.43) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL2922890 | 0.71 | ALDH1A1 (0.48) | KMT2ATSHRMAPTSMN1; SMN2CETP | |
| SCHEMBL588859 | 0.71 | ALDH1A1 (0.44) | KMT2ATSHRMAPTSMN1; SMN2CETP | |
| SCHEMBL4071055 | 0.71 | CETP (0.36) | KMT2ATSHRMAPTSMN1; SMN2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114878-B2 | 6,7-dihydrothieno[3,2-d]pyrimidine for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-14 | — | — | US | disclosed |