SCHEMBL5885406

SCHEMBL5885406

Cc1ccccc1-c1cc(Cl)c(-c2ccccc2)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.50
CSNK2A1 P68400 2/20 0.46
PLA2G7 Q13093 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ESR2 Q92731 1/20 0.41
KDM4E B2RXH2 1/20 0.41
FTO Q9C0B1 1/20 0.40
HSD11B1 P28845 2/20 0.40
CYP2B6 P20813 1/20 0.39
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
HTR7 P34969 1/20 0.39
PRKAB2 O43741 1/20 0.38
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27142057 0.81 CYP2A6 (0.50) CYP2A6CSNK2A1NPC1ALDH1A1HPGD
SCHEMBL20831934 0.80 CA12 (0.46) CYP2A6PLA2G7NPC1HPGDTSHR
SCHEMBL2934305 0.78 AHR (0.58) CYP2A6CSNK2A1NPC1ALDH1A1HPGD
SCHEMBL1556561 0.78 ALDH1A1 (0.50) CYP2A6NPC1ALDH1A1HPGDTSHR
SCHEMBL29420036 0.78 AHR (0.58) CYP2A6CSNK2A1NPC1ALDH1A1HPGD
SCHEMBL29706107 0.78 ESR2 (0.54) CYP2A6NPC1ALDH1A1HPGDTSHR
SCHEMBL616 0.78 ESR2 (0.54) CYP2A6NPC1ALDH1A1HPGDTSHR
Chlorobenzene SCHEMBL28396524 0.77 TSHR (0.50) CYP2A6NPC1ALDH1A1HPGDTSHR
Hydrogen Sulfide SCHEMBL5139770 0.76 AHR (0.56) CYP2A6CSNK2A1NPC1ALDH1A1HPGD
Water SCHEMBL7781910 0.76 ALDH1A1 (0.48) CYP2A6NPC1ALDH1A1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US disclosed
EP-1232225-B1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-01 EP disclosed
EP-1232225-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES Covion Organic Semiconductors GmbH (DE) 2002-08-21 EP disclosed
WO-2001034722-A1 SUBSTITUTED POLY(ARYLENE VINYLENES), METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN ELECTROLUMINESCENT DEVICES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2001-05-17 WO disclosed