⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL3607910 | 0.93 | ALDH1A1 (0.57) | — | |
| Chloromethane SCHEMBL774036 | 0.87 | — | — | |
| Alcohol SCHEMBL28968938 | 0.87 | ALDH1A1 (0.50) | — | |
| Hexane SCHEMBL9152574 | 0.84 | ALDH1A1 (0.47) | — | |
| Heptane SCHEMBL8040709 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL503396 | 0.82 | — | — | |
| SCHEMBL6223 | 0.82 | — | — | |
| SCHEMBL8679785 | 0.82 | ALDH1A1 (1.00) | — | |
| Methylene Chloride SCHEMBL1249920 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL3664027 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114258394-B | Crystal form of oncogenic fusion kinase inhibitor and application thereof | 南京再明医药有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-115397426-B | Ebutinib glucolactone co-crystal and preparation method thereof | 天津睿创康泰生物技术有限公司 | 2024-02-09 | — | — | CN | claimed |
| US-20240043430-A1 | CRYSTAL FORM OF CASEIN KINASE 1e INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2024-02-08 | — | — | US | claimed |
| EP-4269412-A1 | CRYSTAL FORM OF CASEIN KINASE 1E INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2023-11-01 | — | — | EP | claimed |
| CN-111868049-B | Process for preparing somatostatin modulators | 克林提克斯医药股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115397426-A | Ibutotinib glucolactone eutectic and preparation method thereof | 天津睿创康泰生物技术有限公司 | 2022-11-25 | — | — | CN | claimed |
| EP-4023648-A1 | CRYSTAL OF CARCINOGENIC FUSED KINASE INHIBITOR AND APPLICATIONS THEREOF | Simcere Pharmaceutical Co. Ltd. (CN) | 2022-07-06 | — | — | EP | claimed |
| CN-114685566-A | Benzene arsenic oxide crystal form I, crystal form II and crystal form III and preparation method thereof | 江苏挪贝肽医药科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114656468-A | Crystal form of casein kinase 1 epsilon inhibitor, preparation method and application thereof | 杭州和正医药有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-114258394-A | Crystal form of oncogenic fusion kinase inhibitor and application thereof | 先声药业有限公司 | 2022-03-29 | — | — | CN | claimed |
| US-20210087165-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2021-03-25 | — | — | US | claimed |
| WO-2021037156-A1 | CRYSTAL OF CARCINOGENIC FUSED KINASE INHIBITOR AND APPLICATIONS THEREOF | 南京明德新药研发有限公司 | 2021-03-04 | — | — | WO | claimed |
| EP-3740475-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. (US) | 2020-11-25 | — | — | EP | claimed |
| CN-111868049-A | Methods of making somatostatin modulators | 克林提克斯医药股份有限公司 | 2020-10-30 | — | — | CN | claimed |
| US-20200048219-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2020-02-13 | — | — | US | claimed |
| WO-2019143718-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. (US) | 2019-07-25 | — | — | WO | claimed |
| US-8809526-B2 | Synthesis of cyclopentaquinazolines | ONYX PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-20130211082-A1 | Synthesis of Cyclopentaquinazolines | ONYX PHARMACEUTICALS, INC. (US) | 2013-08-15 | — | — | US | claimed |
| US-8314145-B2 | High purity 17α-cyanomethyl-17β-hydroxy-estra-4,9-diene-3-one and process for the synthesis thereof | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 2012-11-20 | — | — | US | claimed |
| EP-1963354-B1 | HIGH PURITY 17alfa-CYANOMETHYL-17beta-HYDROXY-ESTRA-4,9-DIENE-3-ONE AND PROCESS FOR THE SYNTHESIS THEREOF | RICHTER GEDEON NYRT (HU) | 2009-12-09 | — | — | EP | claimed |