Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49039 | 0.83 | — | — | |
| Methylene Chloride SCHEMBL58857 | 0.80 | — | — | |
| SCHEMBL29989468 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27895817 | 0.79 | — | — | |
| Methyl Alcohol SCHEMBL6261246 | 0.75 | — | — | |
| Methylene Chloride SCHEMBL3607910 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1 | |
| Benzene SCHEMBL28325455 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9176600 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| Alcohol SCHEMBL28968938 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1 | |
| Ethyl Chloride SCHEMBL28037793 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294725-A | Asymmetric synthesis method for natural products Aculeatins A, B, D and 6-epi-Aculeatin D | UNIV JIANGXI NORMAL SCI & TECH | 2016-02-03 | — | — | CN | claimed |
| CN-110845433-A | Method for preparing high-purity (R) -4-formyl-2, 2-dimethyl-3-oxazolinyl carboxylic acid tert-butyl ester | 爱斯特（成都）生物制药股份有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-105294725-A | Asymmetric synthesis method for natural products Aculeatins A, B, D and 6-epi-Aculeatin D | UNIV JIANGXI NORMAL SCI & TECH | 2016-02-03 | — | — | CN | disclosed |
| EP-2722333-A1 | Spiro-indole derivatives for the treatment of parasitic diseases. | Novartis AG (CH) | 2014-04-23 | — | — | EP | disclosed |
| EP-2285808-B1 | SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2013-11-20 | — | — | EP | disclosed |
| US-8399453-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-03-19 | — | — | US | disclosed |
| US-20110275613-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2011-11-10 | — | — | US | disclosed |
| US-8053442-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-11-08 | — | — | US | disclosed |
| EP-2285808-A1 | SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES | Novartis AG (CH) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009132921-A1 | SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2009-11-05 | — | — | WO | disclosed |
| US-20090275560-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275560-A1 | ORGANIC COMPOUNDS | OTC, PC, OAT | ALDH1A1 449/4885TSHR 4271/4885TDP1 1933/4885 |
| US-20110275613-A1 | ORGANIC COMPOUNDS | OTC, PC, OAT | ALDH1A1 449/4885TSHR 4260/4885TDP1 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.