Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853140 | 1.00 | CA12 (0.61) | CA12CA1CA2CA9NAAA | |
| SCHEMBL10851189 | 0.97 | — | — | |
| SCHEMBL10849187 | 0.90 | — | — | |
| SCHEMBL28241458 | 0.82 | CA12 (0.64) | CA12CA1CA2CA9NAAA | |
| SCHEMBL4877947 | 0.80 | NAAA (0.64) | CA12CA1CA2CA9NAAA | |
| SCHEMBL4875998 | 0.80 | NAAA (0.64) | CA12CA1CA2CA9NAAA | |
| SCHEMBL11260431 | 0.80 | CA12 (0.61) | CA12CA1CA2CA9NAAA | |
| SCHEMBL4881001 | 0.80 | NAAA (0.64) | CA12CA1CA2CA9NAAA | |
| SCHEMBL21063148 | 0.80 | CA12 (0.61) | CA12CA1CA2CA9NAAA | |
| SCHEMBL3670555 | 0.80 | CA12 (0.61) | CA12CA1CA2CA9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7004979-B2 | Dyeing composition comprising at least one diaminopyrazole oxidation base and at least one pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2006-02-28 | — | — | US | claimed |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | L'OREAL S.A. (FR) | 2004-12-02 | — | — | US | claimed |
| EP-0891181-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2003-05-14 | — | — | EP | claimed |
| US-6551360-B2 | Pyrazoline-3,5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | VIDAL LAURENT (FR) | 2003-04-22 | — | — | US | claimed |
| EP-0889718-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-09-18 | — | — | EP | claimed |
| EP-0900074-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | L' OREAL S.A. | 2002-01-24 | — | — | US | claimed |
| US-6340372-B1 | Compositions for dyeing keratin fibers containing S-oxide-thiazolo-azoles and/or S,S-dioxide-thiazolo-azoles; their use for dyeing as couplers, method of dyeing | L'OREAL S.A. (FR) | 2002-01-22 | — | — | US | claimed |
| US-20010020309-A1 | Compositions for dyeing keratinous fibres, containing pyrrolo-azoles; use as couplers; method of dyeing | L'OREAL S.A. | 2001-09-13 | — | — | US | claimed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | claimed |
| US-6165229-A | Imidazoloazole-containing compositions for dyeing keratin fibers; their use in dyeing as couplers; dyeing process | L'OREAL (FR) | 2000-12-26 | — | — | US | claimed |
| US-6139589-A | HAIR DYES | L'OREAL S.A. (FR) | 2000-10-31 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6063136-A | Compositions containing pyrrolo-oxazole couplers for dyeing keratin fibers and dyeing methods | L'OREAL S.A. (FR) | 2000-05-16 | — | — | US | claimed |
| EP-0893985-B1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING IMIDAZOLO-AZOLE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | OREAL (FR) | 2000-04-12 | — | — | EP | claimed |
| EP-0900074-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1999-03-10 | — | — | EP | claimed |
| EP-0888109-A1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | L'OREAL (FR) | 1999-01-07 | — | — | EP | claimed |
| WO-1997035550-A1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | L'OREAL (FR) | 1997-10-02 | — | — | WO | claimed |
| WO-1997035553-A1 | KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRAZOLIN-3,5-DIONE COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHOD | L'OREAL (FR) | 1997-10-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020309-A1 | Compositions for dyeing keratinous fibres, containing pyrrolo-azoles; use as couplers; method of dyeing | KRT18, KAT7, CBR3 | CA12 1094/4885CA1 1412/4885CA2 971/4885 |
| US-20020007523-A1 | Compositions for dyeing keratinous fibres, containing pyrazolo-azoles; their use for dyeing, as couplers; method of dyeing | KRT18, ZYX, CBR3 | CA12 1134/4885CA1 1336/4885CA2 1273/4885 |
| US-20040237220-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base and a pyrazolo-azole coupling agent | KRT18, PPOX, NOX5 | CA12 742/4885CA1 732/4885CA2 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.