Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salverine SCHEMBL29360867 | 0.86 | ALDH1A1 (0.70) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| Salverine SCHEMBL25064 | 0.86 | ALDH1A1 (0.70) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| Salverine SCHEMBL29375616 | 0.85 | ALDH1A1 (0.68) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11338177 | 0.79 | ALDH1A1 (0.76) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11671640 | 0.78 | ALDH1A1 (0.74) | KDM4ELMNAALDH1A1KMT2AMCHR1 | |
| SCHEMBL3500700 | 0.76 | MCHR1 (0.59) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL31465587 | 0.75 | SCN1A (0.60) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10066976 | 0.75 | RXFP1 (0.64) | KDM4ELMNAALDH1A1KMT2AMAPT | |
| SCHEMBL11754716 | 0.74 | MCHR1 (0.57) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL3500563 | 0.74 | MCHR1 (0.59) | KDM4ELMNAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026360-B1 | Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients | INPHARMA S.A. (CH) | 2006-04-11 | — | — | US | disclosed |