SCHEMBL5886441

SCHEMBL5886441

CCCC1CCC(CCC2CCC(c3ccc([N+](=O)[O-])c(F)c3)CC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.45
MAPT P10636 8/20 0.43
ALDH1A1 P00352 6/20 0.43
LMNA P02545 4/20 0.43
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
THRB P10828 1/20 0.35
GPR174 Q9BXC1 2/20 0.33
GAA P10253 2/20 0.33
GLA P06280 1/20 0.33
ESR2 Q92731 1/20 0.33
HIF1A Q16665 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886438 1.00 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNAATM
SCHEMBL5886466 0.95 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAATM
SCHEMBL5886470 0.95 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAATM
SCHEMBL5886460 0.95 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAATM
SCHEMBL239105 0.85 TDP1 (0.56) MAPTALDH1A1LMNAATMTDP1
SCHEMBL5886535 0.83 CYP2C9 (0.42) CYP2C9MAPTALDH1A1LMNAMAPK1
SCHEMBL5886540 0.83 CYP2C9 (0.42) CYP2C9MAPTALDH1A1LMNAMAPK1
SCHEMBL7065865 0.82 ATM (0.34) CYP2C9MAPTALDH1A1LMNAATM
SCHEMBL10929436 0.81 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMAPK1
SCHEMBL10929444 0.81 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-7112355-B2 Active matrix type liquid crystal display apparatus HITACHI LTD. (JP) 2006-09-26 US disclosed
US-20050084623-A1 Active matrix type liquid crystal display apparatus IPS ALPHA SUPPORT CO., LTD. (JP) 2005-04-21 US disclosed
US-6849309-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2005-02-01 US disclosed
US-6830787-B1 Active matrix liquid crystal display apparatus HITACHI, LTD. (JP) 2004-12-14 US disclosed
US-6649226-B2 Mixture containing dissociating materials; controlling static electricity NEC LCD TECHNOLOGIES, LTD. (JP) 2003-11-18 US disclosed
US-20030201422-A1 Active matrix type liquid crystal display apparatus HITACHI DISPLAYS, LTD. (JP) 2003-10-30 US disclosed
US-20020039162-A1 ACTIVE MATRIX TYPE LIQUID CRYSTAL DISPLAY APPARATUS OHE MASAHITO (JP) 2002-04-04 US disclosed
US-20020028305-A1 Liquid crystal material and liquid crystal display GETNER FOUNDATION LLC 2002-03-07 US disclosed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP disclosed
US-6011606-A Parallel field active matrix type liquid crystal display using liquid crystal having particular electrical properties HITACHI, LTD. (JP) 2000-01-04 US disclosed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP disclosed