Sugi Predict

Sugi Predict / Compounds / SCHEMBL239105

SCHEMBL239105

SCHEMBL239105

O=[N+]([O-])c1ccc(C2CC2)cc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ ALDH1A1 P00352 5/20 0.42
▸ HIF1A Q16665 2/20 0.42
▸ VCAM1 P19320 1/20 0.40
▸ TSHR P16473 4/20 0.39
▸ MAPK1 P28482 3/20 0.39
▸ MAPT P10636 6/20 0.38
▸ GAA P10253 3/20 0.38
▸ GLA P06280 1/20 0.38
▸ CYP3A4 P08684 2/20 0.36
▸ ESPL1 Q14674 1/20 0.36
▸ CASP6 P55212 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ MITF O75030 1/20 0.35
▸ GPR35 Q9HC97 1/20 0.34
▸ TP53 P04637 1/20 0.33
▸ HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1970805 0.93 ATM (0.53) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL29653738 0.93 ATM (0.53) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL2653166 0.86 ALDH1A1 (0.55) TDP1ATMALDH1A1HIF1AVCAM1
SCHEMBL5886438 0.85 CYP2C9 (0.45) TDP1ATMALDH1A1HIF1AMAPK1
SCHEMBL5886441 0.85 CYP2C9 (0.45) TDP1ATMALDH1A1HIF1AMAPK1
SCHEMBL5886466 0.83 CYP2C9 (0.43) TDP1ATMALDH1A1MAPK1MAPT
SCHEMBL5886470 0.83 CYP2C9 (0.43) TDP1ATMALDH1A1MAPK1MAPT
SCHEMBL5886460 0.83 CYP2C9 (0.43) TDP1ATMALDH1A1MAPK1MAPT
SCHEMBL19021742 0.81 ATM (0.41) TDP1ATMALDH1A1HIF1ATSHR
SCHEMBL10252368 0.79 ALDH1A1 (0.51) TDP1ATMALDH1A1HIF1AVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663630-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR LG Chem, Ltd. (KR) 2025-12-17 — — EP disclosed
US-12479845-B2 Imidazopyridine derivative compounds and use of same HANMI PHARM. CO., LTD. (KR) 2025-11-25 — — US disclosed
WO-2025217212-A1 MAC1 INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-10-16 — — WO disclosed
CN-111848598-B Heterocyclic compound, application thereof and composition containing same 健艾仕生物医药有限公司 2024-12-10 — — CN disclosed
WO-2024201308-A1 NOVEL BENZIMIDAZOLONE DERIVATIVE COMPOUND AS AUTOTAXIN INHIBITOR 주식회사 엘지화학 2024-10-03 — — WO disclosed
CN-113365996-B Imidazole pyridine derivative compound and pharmaceutical composition 韩美药品株式会社 2024-09-03 — — CN disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 — — US disclosed
US-20230099441-A1 HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME GENEROS BIOPHARMA LTD. (CN) 2023-03-30 — — US disclosed
CN-115611897-A Compounds as RSK2 inhibitors and uses thereof 南京圣和药业股份有限公司 2023-01-17 — — CN disclosed
US-20220098205-A1 IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME HANMI PHARM. CO., LTD. (KR) 2022-03-31 — — US disclosed
WO-2009085983-A1 5-ANILINOIMIDAZOPYRIDINES AND METHODS OF USE GENENTECH, INC. (US) 2009-07-09 — — WO disclosed
CN-101448495-A To M1Benzimidazole compound with active receptor and application thereof in medicines GLAXO GROUP LTD (GB) 2009-06-03 — — CN disclosed
EP-2004182-A1 BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE GLAXO GROUP LIMITED (GB) 2008-12-24 — — EP disclosed
US-20080306112-A1 Benzimidazolones Which Have Activity at M1 Receptor GLAXO GROUP LIMITED (GB) 2008-12-11 — — US disclosed
US-20080306112-A1 Benzimidazolones Which Have Activity at M1 Receptor GLAXO GROUP LIMITED (GB) 2008-12-11 — — US disclosed
US-20080306112-A1 Benzimidazolones Which Have Activity at M1 Receptor GLAXO GROUP LIMITED (GB) 2008-12-11 — — US disclosed
EP-1937670-A1 BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT M1 RECEPTOR GLAXO GROUP LIMITED (GB) 2008-07-02 — — EP disclosed
WO-2007107565-A1 BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE GLAXO GROUP LIMITED (GB) 2007-09-27 — — WO disclosed
WO-2007036711-A1 BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT Ml RECEPTOR GLAXO GROUP LIMITED (GB) 2007-04-05 — — WO disclosed
WO-2007036711-A1 BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT Ml RECEPTOR GLAXO GROUP LIMITED (GB) 2007-04-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099441-A1 HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME STAT5A, STAT5B, JAK2 TDP1 4627/4885ATM 2087/4885ALDH1A1 3812/4885
US-20220098205-A1 IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME KDM1A, KDM1B, KDM2A TDP1 359/4885ATM 1336/4885ALDH1A1 404/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS TDP1 3922/4885ATM 4146/4885ALDH1A1 2858/4885
US-20080306112-A1 Benzimidazolones Which Have Activity at M1 Receptor CHRM1, CHRM2, CHRM4 TDP1 2924/4885ATM 2389/4885ALDH1A1 839/4885
US-12479845-B2 Imidazopyridine derivative compounds and use of same KDM1A, KDM1B, KDM2A TDP1 359/4885ATM 1336/4885ALDH1A1 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.