SCHEMBL588653

SCHEMBL588653

C=CC(=O)N(C(O)CC)C(O)CC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
ALDH1A1 P00352 3/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL589046 0.83 TSHR (0.34) TSHRALDH1A1ZDHHC20ZDHHC2TDP1
SCHEMBL28099880 0.80 ALDH1A1 (0.36) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL589147 0.79 TSHR (0.41) TSHRZDHHC20ZDHHC2MAPK1
SCHEMBL8071175 0.79 ALDH1A1 (0.32) TSHRALDH1A1MAPK1TDP1
SCHEMBL8641760 0.78 TSHR (0.35) TSHRALDH1A1ZDHHC20
SCHEMBL429457 0.77 TSHR (0.42) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL7943792 0.76 ALDH1A1 (0.36) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL157071 0.75 TSHR (0.39) TSHRALDH1A1ZDHHC20ZDHHC2MAPK1
SCHEMBL9004322 0.74 ALDH1A1 (0.34) TSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL1041496 0.73 TSHR (0.37) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317250-A1 RADIATION-CURABLE AQUEOUS POLYURETHANE DISPERSIONS COVESTRO (NETHERLANDS) B.V. (NL) 2021-10-14 US claimed
EP-3820924-A1 RADIATION-CURABLE AQUEOUS POLYURETHANE DISPERSIONS DSM IP Assets B.V. (NL) 2021-05-19 EP claimed
WO-2020011805-A1 RADIATION-CURABLE AQUEOUS POLYURETHANE DISPERSIONS DSM IP ASSETS B.V. (NL) 2020-01-16 WO claimed
US-20250276937-A1 DISPERSION OF (METH)ACRYLATE COPOLYMER AND USE THEREOF AS A BINDER FOR CEMENTITIOUS MATERIALS BASF SE (DE) 2025-09-04 US disclosed
EP-4519226-A1 DISPERSION OF (METH)ACRYLATE COPOLYMER AND USE THEREOF AS A BINDER FOR CEMENTITIOUS MATERIALS BASF SE (DE) 2025-03-12 EP disclosed
EP-2960314-B1 POLISHING COMPOSITION AND METHOD FOR MANUFACTURING POLISHED ARTICLE FUJIMI INC (JP) 2024-06-26 EP disclosed
EP-3159915-B1 METHOD FOR POLISHING SILICON WAFER, POLISHING COMPOSITION, AND POLISHING COMPOSITION SET FUJIMI INC (JP) 2023-12-06 EP disclosed
WO-2023213719-A1 DISPERSION OF (METH)ACRYLATE COPOLYMER AND USE THEREOF AS A BINDER FOR CEMENTITIOUS MATERIALS BASF SE (DE) 2023-11-09 WO disclosed
US-20230348653-A1 RADIATION-CURABLE AQUEOUS POLYURETHANE DISPERSIONS COVESTRO (NETHERLANDS) B.V. (NL) 2023-11-02 US disclosed
EP-4087884-A1 RADIATION-CURABLE AQUEOUS POLYURETHANE DISPERSIONS Covestro (Netherlands) B.V. (NL) 2022-11-16 EP disclosed
US-20220332867-A1 HYDROXYALKYLAMIDE FUNCTIONALIZED ACRYLIC POLYMERS AND PROCESS FOR MANUFACTURING THEM POLIRESIN S R L (IT) 2022-10-20 US disclosed
US-8114819-B2 Polymers for oilfield applications BAKER HUGHES INCORPORATED (US) 2012-02-14 US disclosed
US-20100105580-A1 Polymers For Oilfield Applications BJ SERVICES COMPANY (US) 2010-04-29 US disclosed
US-6800788-B2 FLUORINE-CONTAINING COMPOUNDS, AND POLYMERS DERIVED THEREFROM, FOR USE IN COMPOSITIONS USED FOR TREATING TEXTILE SUBSTRATES. ALSO PROVIDED ARE METHODS OF MAKING FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM, COMPOSITIONS HONEYWELL INTERNATIONAL INC. 2004-10-05 US disclosed
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-06-12 US disclosed
EP-0830208-B1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECH CORP (US) 2000-07-26 EP disclosed
EP-0830208-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS Cytec Technology Corp. (US) 1998-03-25 EP disclosed
WO-1996040438-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
US-5533626-A FROTH FLOTATION USING POLYMER MIXTURE OF POLYSACCHARIDES ANDACRYLAMIDE POLYMER CYTEC TECHNOLOGY CORP. (US) 1996-07-09 US disclosed
US-5531330-A Method of depressing non-sulfide silicate gangue minerals CYTEC TECHNOLOGY CORP. (US) 1996-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom WASF2, NOTUM, NEFM TSHR 3996/4885ALDH1A1 802/4885ZDHHC20 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.