Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178031 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL7110107 | 0.78 | GRIK1 (0.31) | — | |
| SCHEMBL429457 | 0.76 | TSHR (0.42) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL588653 | 0.76 | TSHR (0.37) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL157071 | 0.74 | TSHR (0.39) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL9004322 | 0.72 | ALDH1A1 (0.34) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL15841446 | 0.72 | TSHR (0.38) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL2232029 | 0.71 | ALDH1A1 (0.33) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL1007133 | 0.69 | — | — | |
| SCHEMBL4781625 | 0.68 | TSHR (0.39) | ALDH1A1TSHRZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258275-B1 | Affinity macroligands | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2001-07-10 | — | — | US | disclosed |
| EP-0126363-B1 | USE OF COPOLYMER FROM ESTERS AND AMIDES OF ACRYLIC AND/OR METHACRYLIC ACIDS AS POUR POINT DEPRESSANTS IN PARAFFIN SOLUTIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-12-03 | — | — | EP | disclosed |
| EP-0126363-A1 | Use of copolymer from esters and amides of acrylic and/or methacrylic acids as pour point depressants in paraffin solutions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-11-28 | — | — | EP | disclosed |