Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 1.00 |
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA1 | P00915 | 8/20 | 1.00 |
| ▸ | CA2 | P00918 | 8/20 | 1.00 |
| ▸ | CA9 | Q16790 | 8/20 | 1.00 |
| ▸ | MMP8 | P22894 | 5/20 | 1.00 |
| ▸ | MMP1 | P03956 | 4/20 | 1.00 |
| ▸ | MMP3 | P08254 | 3/20 | 1.00 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Cyclohexylamino)Carbonylphosphonic Acid SCHEMBL13986865 | 1.00 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| (Cyclohexylamino)Carbonylphosphonic Acid SCHEMBL4850185 | 0.98 | MMP2 (0.96) | MMP2CA12CA1CA2CA9 | |
| (Cyclopentylamino)Carbonylphosphonic Acid SCHEMBL4846602 | 0.98 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| (Cyclohexylamino)Carbonylphosphonic Acid SCHEMBL4850182 | 0.77 | MMP2 (0.62) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10376229 | 0.76 | MMP2 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4854264 | 0.76 | MMP2 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10698154 | 0.76 | MMP2 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL5151614 | 0.72 | MMP2 (0.57) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL5058559 | 0.72 | MMP2 (0.57) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL24308699 | 0.72 | EPHX1 (1.00) | EPHX1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101864-B1 | Compositions comprising oxophosphonate-based metalloproteinase inhibitors | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-05 | — | — | US | claimed |
| EP-1223945-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-07-24 | — | — | EP | claimed |
| WO-2001026661-A1 | COMPOSITIONS COMPRISING OXOPHOSPHONATE-BASED METALLOPROTEINASE INHIBITORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-04-19 | — | — | WO | claimed |