Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.61 |
| ▸ | MMP1 | P03956 | 2/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Cyclohexylamino)Carbonylphosphonic Acid SCHEMBL13986865 | 0.76 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| (Cycloheptylamino)Carbonylphosphonic Acid SCHEMBL5886552 | 0.76 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| (Cyclohexylamino)Carbonylphosphonic Acid SCHEMBL4850185 | 0.74 | MMP2 (0.96) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL10698154 | 0.74 | MMP2 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4854264 | 0.74 | MMP2 (0.61) | MMP2CA12CA1CA2CA9 | |
| (Cyclopentylamino)Carbonylphosphonic Acid SCHEMBL4846602 | 0.73 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL5151614 | 0.71 | MMP2 (0.57) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL24022707 | 0.71 | EPHX1 (0.55) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL18823623 | 0.71 | EPHX1 (0.55) | MMP2CA12CA1CA2CA9 | |
| Phosphoric Acid SCHEMBL8573215 | 0.69 | ALDH1A1 (0.67) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388732-A2 | Pentasubstituted phenyls | BAYER AG (DE) | 1990-09-26 | — | — | EP | disclosed |
| EP-0378850-A2 | Substituted pyrido(2,3-d) pyrimidines | BAYER AG (DE) | 1990-07-25 | — | — | EP | disclosed |