Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 5/20 | 0.57 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.57 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLR1A | O95602 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886330 | 0.80 | RAD52 (0.64) | RAD52SMARCA2UHRF1AOX1KDM4E | |
| SCHEMBL7066503 | 0.79 | RAD52 (0.58) | RAD52SMARCA2UHRF1AOX1MAPT | |
| SCHEMBL29634211 | 0.78 | RAD52 (0.85) | RAD52SMARCA2UHRF1AOX1KDM4E | |
| SCHEMBL8224795 | 0.78 | RAD52 (0.85) | RAD52SMARCA2UHRF1AOX1KDM4E | |
| SCHEMBL5886339 | 0.78 | RAD52 (0.45) | RAD52SMARCA2UHRF1MAPTLMNA | |
| SCHEMBL5886244 | 0.78 | RAD52 (0.67) | RAD52SMARCA2UHRF1AOX1KDM4E | |
| SCHEMBL5886260 | 0.78 | KMT2A (0.51) | RAD52SMARCA2MAPTLMNAKDM4E | |
| SCHEMBL5886543 | 0.77 | RAD52 (0.61) | RAD52SMARCA2UHRF1AOX1KDM4E | |
| Hydrochloric Acid SCHEMBL10866302 | 0.77 | RAD52 (0.87) | RAD52SMARCA2UHRF1AOX1HPGD | |
| SCHEMBL7573561 | 0.77 | RAD52 (0.68) | RAD52SMARCA2UHRF1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132419-B2 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2006-11-07 | — | — | US | claimed |