Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 6/20 | 0.58 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.58 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.39 |
| ▸ | POLR1A | O95602 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886319 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5886330 | 0.80 | RAD52 (0.64) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| SCHEMBL7063204 | 0.79 | RAD52 (0.69) | RAD52SMARCA2UHRF1AOX1HRH4 | |
| SCHEMBL5886580 | 0.79 | RAD52 (0.57) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| SCHEMBL29634211 | 0.79 | RAD52 (0.85) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| SCHEMBL8224795 | 0.79 | RAD52 (0.85) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| SCHEMBL5886244 | 0.79 | RAD52 (0.67) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10866302 | 0.78 | RAD52 (0.87) | RAD52SMARCA2UHRF1AOX1PTK2 | |
| SCHEMBL5886543 | 0.78 | RAD52 (0.61) | RAD52SMARCA2UHRF1AOX1ALDH1A1 | |
| SCHEMBL5886272 | 0.76 | RAD52 (0.70) | RAD52SMARCA2UHRF1AOX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | XENOVA LIMITED (GB) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139409-A1 | Benzo[A] [phenazin-11-carboxamide derivatives and their use as joint inhibitors of topomerase I and II | TOP1, TOP2A, TOP2B | RAD52 60/4885SMARCA2 1456/4885UHRF1 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.