Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 5/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | TEK | Q02763 | 2/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886580 | 0.78 | RAD52 (0.57) | RAD52SMARCA2UHRF1MAPTADORA2A | |
| SCHEMBL5886260 | 0.77 | KMT2A (0.51) | RAD52SMARCA2MEN1KMT2APOLB | |
| SCHEMBL23583616 | 0.77 | RAD52 (0.48) | RAD52SMARCA2AURKALCKMET | |
| SCHEMBL29406105 | 0.77 | RAD52 (0.48) | RAD52SMARCA2AURKALCKMET | |
| SCHEMBL5886271 | 0.76 | ALDH1A1 (0.54) | RAD52SMARCA2MEN1KMT2APOLB | |
| SCHEMBL5886396 | 0.76 | RAD52 (0.47) | RAD52SMARCA2UHRF1MEN1KMT2A | |
| SCHEMBL5886288 | 0.76 | RAD52 (0.47) | RAD52SMARCA2UHRF1MEN1KMT2A | |
| SCHEMBL5886455 | 0.70 | KDM4E (0.47) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL5886330 | 0.69 | RAD52 (0.64) | RAD52SMARCA2UHRF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7066503 | 0.69 | RAD52 (0.58) | RAD52SMARCA2UHRF1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132419-B2 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2006-11-07 | — | — | US | claimed |