Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887428 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886700 | 0.92 | MGLL (0.42) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5887316 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886964 | 0.92 | MAPK8 (0.45) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886773 | 0.92 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886882 | 0.92 | MAPT (0.43) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5887019 | 0.91 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886747 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5887099 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA | |
| SCHEMBL5886763 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019002-B2 | Substituted on 8th position with benzoic acid, ester or amide groups; anticancer agents | PHARMACIA & UPJOHN, S.P.A. (IT) | 2006-03-28 | — | — | US | disclosed |