Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.30 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.30 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718550 | 0.83 | PLA2G1B (0.40) | ALDH1A1HTT | |
| SCHEMBL4714556 | 0.81 | HTT (0.36) | GGPS1FDPSPSEN1PSEN2APH1B | |
| SCHEMBL4718724 | 0.79 | ATP4A (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4717663 | 0.77 | GGPS1 (0.37) | GGPS1FDPSALDH1A1 | |
| SCHEMBL4716769 | 0.76 | FEN1 (0.36) | GGPS1FDPS | |
| SCHEMBL4720761 | 0.75 | ROCK2 (0.39) | ALDH1A1 | |
| SCHEMBL4717668 | 0.69 | KDM4E (0.36) | GGPS1FDPSALDH1A1 | |
| SCHEMBL4716835 | 0.68 | GGPS1 (0.58) | GGPS1FDPS | |
| SCHEMBL4715662 | 0.68 | NPC1 (0.41) | ALDH1A1 | |
| SCHEMBL14290310 | 0.66 | KDM4E (0.39) | GGPS1FDPSPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071208-B2 | β3 Adrenergic agonists | ELI LILLY AND COMPANY (US) | 2006-07-04 | — | — | US | disclosed |