Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.49 |
| ▸ | FLT1 | P17948 | 15/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14409832 | 0.89 | KDR (0.45) | KDRFLT1MET | |
| SCHEMBL14409934 | 0.88 | KDR (0.44) | KDRFLT1MET | |
| SCHEMBL5240496 | 0.87 | KDR (0.45) | KDRFLT1MET | |
| SCHEMBL5243763 | 0.86 | KDR (0.45) | KDRFLT1MET | |
| SCHEMBL5244749 | 0.85 | KDR (0.47) | KDRFLT1MET | |
| SCHEMBL5242752 | 0.83 | KDR (0.46) | KDRFLT1 | |
| SCHEMBL5240438 | 0.81 | KDR (0.46) | KDRFLT1MET | |
| SCHEMBL5241513 | 0.81 | KDR (0.45) | KDRFLT1MET | |
| SCHEMBL5240135 | 0.80 | KDR (0.43) | KDRFLT1MET | |
| SCHEMBL5240761 | 0.80 | KDR (0.43) | KDRFLT1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045528-B2 | Benzofused heterozryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use | AGOURON PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20040186126-A1 | Benzofused heterozryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use | AGOURON PHARMACEUTICALS, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186126-A1 | Benzofused heterozryl amide derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use | DPYD, DHFR, TYMP | KDR 1885/4885FLT1 1091/4885MET 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.