SCHEMBL5888901

SCHEMBL5888901

C=CCOc1[c]c(OCC=C)cc(OCC=C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 5/20 0.39
CA1 P00915 5/20 0.39
CA9 Q16790 5/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
MAOA P21397 1/20 0.35
GAA P10253 5/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
FGFR1 P11362 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3818350 0.81 MAPT (0.47) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL15067030 0.77 MEN1 (0.39) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL15066324 0.77 MEN1 (0.39) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL3846804 0.76 MAPT (0.42) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL3840978 0.76 HPGD (0.38) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL3844869 0.73 MAPT (0.42) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL15066835 0.72 GAA (0.37) MEN1KMT2AMAOAGAAHPGD
SCHEMBL17460027 0.72 CA12 (0.34) LMNAMAPTSMN1; SMN2CA12CA9
SCHEMBL15939882 0.72 MAPT (0.33) MAPTCA12CA1CA9ADRA2A
SCHEMBL3595767 0.71 ALDH1A1 (0.41) MEN1LMNAMAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US claimed