SCHEMBL5888903

SCHEMBL5888903

C=CCc1cccc2c(O)[c]ccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.47
GABRB2 P47870 2/20 0.47
KMT2A Q03164 7/20 0.39
MEN1 O00255 6/20 0.39
MAPT P10636 4/20 0.39
MAPK1 P28482 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
AKR1B1 P15121 1/20 0.38
GAA P10253 4/20 0.38
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37
MAP4K4 O95819 1/20 0.37
RET P07949 1/20 0.37
IGF1R P08069 1/20 0.37
MET P08581 1/20 0.37
PIM1 P11309 1/20 0.37
LTK P29376 1/20 0.37
KDR P35968 1/20 0.37
MAPK8 P45983 1/20 0.37
MAPK9 P45984 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831594 0.80 GABRA1 (0.56) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL31619949 0.80 GABRA1 (0.56) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL5888928 0.79 GABRA1 (0.42) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL21409555 0.77 GABRA1 (0.55) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL1638775 0.77 GABRA1 (0.50) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL5889014 0.75 GABRA1 (0.46) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL19856499 0.72 GABRA1 (0.42) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL393930 0.72 GABRA1 (0.40) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL5831736 0.71 GABRA1 (0.45) GABRA1GABRB2KMT2AMEN1MAPT
SCHEMBL9312981 0.71 GABRA1 (0.66) GABRA1GABRB2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US claimed