Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176260 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5888903 | 0.77 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL7761703 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL3661576 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL4789832 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5091335 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL1515067 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5454296 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL5889014 | 0.75 | GABRA1 (0.46) | GABRA1GABRB2AKR1B1KMT2AMEN1 | |
| SCHEMBL393930 | 0.74 | GABRA1 (0.40) | GABRA1GABRB2AKR1B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207691-A1 | Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury | UNIVERSITY OF PITTSBURGH - OF T | 2020-07-02 | — | — | US | claimed |
| CN-209784571-U | High-definition lens with Abbe number of 45 | 河南达人视界眼镜有限公司 | 2019-12-13 | — | — | CN | claimed |
| CN-109917497-A | A kind of high definition eyeglass of Abbe number 45 | 河南达人视界眼镜有限公司 | 2019-06-21 | — | — | CN | claimed |
| US-20180312455-A1 | Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-11-01 | — | — | US | claimed |
| CN-107974080-A | Polyamide moulding composition and the sandwich construction being made from it | EMS专利股份公司 | 2018-05-01 | — | — | CN | claimed |
| US-20150136603-A1 | WATER-SOLUBLE, UV-ABSORBING AND/OR FLOURESCENT COMPONENTS WITH VERY HIGH ISOELECTRIC POINTS | TEXAS A & M UNIV SYS (US) | 2015-05-21 | — | — | US | claimed |
| WO-2012109527-A2 | CLASS OF HDAC INHIBITORS EXPANDS THE RENAL PROGENITOR CELLS POPULATION AND IMPROVES THE RATE OF RECOVERY FROM ACUTE KIDNEY INJURY | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-08-16 | — | — | WO | claimed |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | ACUMEN PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | claimed |
| EP-2194975-A2 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-ß DIFFUSABLE LIGANDS USING A ACYLHYDRAZIDE COMPOUNDS | Acumen Pharmaceuticals, Inc. (US) | 2010-06-16 | — | — | EP | claimed |
| US-20090023912-A1 | Water-soluble, uv-absorbing and/or flourescent components with very high isoelectric points | VIGH GYULA | 2009-01-22 | — | — | US | claimed |
| US-7041388-B1 | Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices | SEMICONDUCTORS GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| WO-2005105910-A2 | WATER-SOLUBLE, UV-ABSORBING AND/OR FLUORESCENT COMPONENTS WITH VERY HIGH ISOELECTRIC POINTS | TEXAS A & M UNIVERSITY SYSTEM (US) | 2005-11-10 | — | — | WO | claimed |
| CN-1175431-C | stable communication cable insulation composition | �������⻯ѧƷ�ع�����˾ | 2004-11-10 | — | — | CN | claimed |
| CN-1534692-A | HYAB type copper core poly olefin insulating aluminium plastic comprehensive shield sleeve broad band communication cable | 区淑莲 | 2004-10-06 | — | — | CN | claimed |
| US-6462034-B1 | MULTIBINDING COMPOUNDS CONTAINING A SYMETRICAL DIAMINOTETRA-ETHERDODECANE RING WITH TWO SECONDARY AMIDE AND ADDITIONAL SUBSTITUENTS; VOLTAGE GATED SODIUM CHANNEL MODULATORS; LONG DURATION | THERAVANCE, INC. | 2002-10-08 | — | — | US | claimed |
| CN-1344418-A | Stabilized telecommunication cable insulation compsn. | CIBA SC HOLDING AG (CH) | 2002-04-10 | — | — | CN | claimed |
| EP-0458984-B1 | NOVEL RESIN, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME | NIPPON OIL CO LTD (JP) | 1995-09-20 | — | — | EP | claimed |
| EP-0566533-A1 | Sulfated vinylphenol polymers, compositions containing sulfated vinylphenol polymers and the use thereof | CIBA-GEIGY AG (CH) | 1993-10-20 | — | — | EP | claimed |
| US-4405736-A | 2,2,6,6-Tetramethyl-4-piperidyl spiro aliphatic ethers and stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | claimed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312455-A1 | Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury | HDAC1, HDAC9, HDAC11 | GABRA1 3842/4885GABRB2 3065/4885AKR1B1 921/4885 |
| US-20110098309-A1 | METHODS OF INHIBITING THE FORMATION OF AMYLOID-BETA DIFFUSABLE LIGANDS USING ACYLHYDRAZIDE COMPOUNDS | APP, APBA1, BACE1 | GABRA1 1313/4885GABRB2 920/4885AKR1B1 1424/4885 |
| US-20200207691-A1 | Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury | HDAC1, HDAC9, HDAC11 | GABRA1 3842/4885GABRB2 3065/4885AKR1B1 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.